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KMID : 0364019720050010001
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Korean Journal of Thoracic and Cardiovascular Surgery
1972 Volume.5 No. 1 p.1 ~ p.7
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Surface Activity in Various Pulmonary Diseases
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Abstract
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0n the study of surface activity in excized lung extracts of various pulmonary diseases, following facts were concluced.
1) The minimum suface tension measured in lung extracts of tuberculous tissue surrounding cavitary lesson was 26.3 dyne/cm and its stability index was 0.53.
2) Macroscopically almost normal lung tissue at a distance of tuberculous lesion in same lobe revealed 21.3 dyne/cm of minimum surface tension in extracts and its stability index showed 0.66. This low surface activity may be due to the chronic pneumonitis microscopically.
3) In the atelectatic lung which had been collapsed by chronic emyema the extracts revealed much higher minimum surface tension in 27.3 dyne/cm and its stability index revealed the least value of 0.47 without correlation of duration of disease.
This suggests that the longstanding collapsed lung may be soon collapsed even after mechanical full expansion because of lack of surfactant. surfactant.
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